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Coefficient of consanguinity automatic calculation

Gain time in drawing and interpreting pedigrees linked to consanguineous marriages. PedigreeXP automatically calculates the coefficient of consanguinity and indicates it with a double-line.

Coefficient of consanguinity is the probability that a pair of alleles belonging to different individuals are the same, given their degree of common ancestry. Oxford Index

The offspring of consanguineous unions may be at increased risk to genetic disorders because of the expression of autosomal recessive gene mutations inherited from a common ancestor. The closer the biological relationship between parents, the greater is the probability that their offspring will inherit identical copies of one or more detrimental recessive mutations.

The coefficient of consanguinity is calculated and analysed to assist health professionals who provide genetic counseling and screening to related couples and their offspring.

It’s important for genetic counselors, geneticists or other health professionals to appropriately document and draw pedigrees of consanguineous marriages if present in the family.

 

PedigreeXP automatically calculates the coefficient of consanguinity.

PedigreeXP automatically calculates the coefficient of consanguinity.

 

More PedigreeXP features.

PC PAL at the ESHG conference

PC PAL team is eager to meet you at the European Human Genetics Conference (ESHG)  which will be held in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG) on May 21-24, 2016 in Barcelona, Spain.

This will be the opportunity to present our PedigreeXP software and its updated features to the great community of ESHG attendees.

Meet PC PAL at ESHG in Barcelona - May 21-24

Meet PC PAL at ESHG in Barcelona – May 21-24

Take a minute to discover the #1 pedigree drawing and managing software and get your free trial!
Our experts will be here to answer all your questions about PedigreeXP integration in medical information systems. To plan a meeting ahead, contact us at sales@pedigreexp.com or call us at 00 33 1 69 53 46 20.
We’re at booth #336!

Check PedigreeXP features

Download a free trial

More on integration

User testimonial

 

Alexander Damette – CHU Besançon (University Hospital) France

(EN | FR)

“PedigreeXP is a time-saving software”

Genetic and onco-genetic counselor, Alexander Damette has been working in genetics for 15 years and for 7 years at the CHU Besançon. He collaborates with a cancer geneticist and a Doctor of Science who tracks people affected by a genetic mutation. He talks about PedigreeXP.

Why PedigreeXP?

“After years of using Cyrillic software, I faced an incompatibility of my Cyrillic files with my computer system. To solve this situation, I started to evaluate different softwares. I finally chose PedigreeXP thanks to which I could keep my precious pedigrees and continue working with all my Cyrillic files. Today, I draw all new pedigrees with PedigreeXP.”

PedigreeXP product benefits

“Fast, intuitive and easy to use, PedigreeXP allows me to design my pedigrees during the consultations.” Furthermore, Mr. Damette highlights an essential quality of the product: the capture and export of BOADICEA data allowing it to simplify the calculation of scores.
Mr. Damette talks about PedigreeXP as a “time-saving software” which he recommends the use.

Download the free trial

 

Alexandre Damette – CHU de Besançon

(EN | FR)

“PedigreeXP est un logiciel de gain de temps”

Conseiller en génétique exerçant en onco-génétique, M. Alexandre Damette travaille dans la génétique depuis 15 ans, dont 7 ans au CHU de Besançon.
Il collabore avec un médecin onco-généticien et une attachée de recherche clinique qui assure le suivi des personnes porteuses d’une mutation génétique.

Pourquoi PedigreeXP ?

“Après plusieurs années d’utilisation du logiciel Cyrillic, j’ai été confronté à une incompatibilité de mes fichiers Cyrillic avec mon système informatique. Face à l’impossibilité d’ouvrir mes fichiers, j’ai évalué différents logiciels. Mon choix s’est porté sur PedigreeXP qui m’a permis de conserver mes précieux arbres généalogiques et de continuer à travailler avec tous mes fichiers Cyrillic. Aujourd’hui, je dessine tous les nouveaux arbres généalogiques avec PedigreeXP.”

Les bénéfices produit de PedigreeXP

“Rapide, intuitif et simple d’utilisation, PedigreeXP me permet de concevoir mes arbres généalogiques durant les consultations.”
Par ailleurs, M. Damette souligne un bénéfice produit primordial : la saisie et l’export des données BOADICEA qui lui permettent de simplifier le calcul des scores.
M. Damette parle de PedigreeXP comme “d’un logiciel de gain de temps” dont il recommande l’utilisation.

Télécharger la version d’essai

Integrate pedigrees into your medical information systems using PedigreeXP


(EN | FR)

PC PAL applications are designed for integration in various IT environments. PedigreeXP is no exception to the rule, whether the integration is in hospital information systems or in specific medical systems. The object implementation approach makes PedigreeXP unique and gives its users high implementation flexibility.

We must not forget that the design or modification of a pedigree is an action that must be performed as efficiently as possible. PedigreeXP favors the design and customization of the pedigrees, as well as their management and graphic restitution, while allowing interfacing with other systems. The very accomplished pedigree design and the high integration capability of PedigreeXP make it the best design software in its class.

PedigreeXP exists in different versions to best meet the different use cases encountered in hospitals.

The professional version allows, with some settings, to automate a direct link with the patient record. PedigreeXP is launched from the patient record, the pedigree is designed and updated with PedigreeXP and directly saved into the patient record. In this version, data can be directly visualized and entered in third-party databases.

The component version allows pedigree visualization in other applications. This is a different approach which emphasizes on data retrieval and on control of access to data. This version is fully compatible with Windows or web applications, PedigreeXP is embedded and driven by other applications.

– Association of pedigrees in patient records
– Saving pedigrees directly into patient records
– Integration in specific medical systems
– Drawing and restitution of pedigrees from a database (genetic or others)
– Import and export data in standard formats
– Drawing and visual rendering of pedigrees in web pages or Windows applications
– Rendering of pedigrees following an external input (eg: web forms)

The standalone version, available online, provides individual users total autonomy in the design and management of their pedigrees. The pedigrees are saved in the native format of the software and shared in PDF format. Pedigrees are manually added in patient records.

These different versions offer a wide variety of integration scenarios to best meet the needs of our customers and software vendors. Use cases are numerous, the list above gives you an overview, I hope it will give you ideas for your projects.

Laurent ROSSAERT – PC PAL
Director of Sales and Marketing
laurent.rossaert@pcpal.eu | LinkedIn

 

PedigreeXP, vos arbres généalogiques intégrés dans vos systèmes d’informations hospitaliers

(EN | FR)

Les logiciels de la société PC PAL sont conçus pour être intégrés dans des environnements informatiques variés. PedigreeXP ne déroge pas à la règle, qu’il s’agisse de systèmes d’informations hospitaliers ou systèmes médicaux spécifiques. L’approche objet mise en œuvre dans PedigreeXP le rend unique et procure à ses usagers une grande latitude de mise en œuvre.

La conception ou la modification d’un arbre est une action qui doit être réalisée le plus efficacement possible. Le logiciel PedigreeXP privilégie la conception, la personnalisation des arbres, leur gestion et leur restitution graphique, tout en permettant l’interfaçage avec d’autres systèmes. La conception d’arbres très aboutie et l’importante capacité d’intégration font de PedigreeXP le meilleur outil de conception dans sa catégorie.

Le logiciel PedigreeXP existe dans différentes versions pour répondre au mieux aux différents cas d’utilisation rencontrés dans les institutions hospitalières et médicales.

La version professionnelle, permet avec quelques paramétrages, d’automatiser un lien direct avec le dossier patient. PedigreeXP est lancé depuis le dossier patient, l’arbre est conçu et mis à jour depuis PedigreeXP puis sauvegardé directement dans le dossier patient. Cette version permet également de lire et d’écrire directement les données de l’arbre dans une base de données tierce.

La version composant permet de visionner des arbres dans une autre application. Cette version procure une approche différente, privilégiant la consultation et le contrôle de l’accès à l’information. Elle fonctionne aussi bien avec des applications web que Windows, PedigreeXP est alors embarqué et piloté par d’autres applications.

– Association d’arbres aux dossiers patients
– Sauvegarde d’arbres directement dans les dossiers patients
– Intégration dans des systèmes informatiques spécifiques
– Dessin et restitution d’arbres à partir d’une base de données (génétique ou non)
– Import et export de données dans des formats standards
– Dessin et restitution d’arbres sous forme visuelle dans des pages web ou des applications
– Restitution d’arbres suite à une saisie externe (ex : formulaires web)

La version autonome de PedigreeXP, accessible en ligne, propose aux utilisateurs individuels une totale autonomie dans la conception et la gestion de leurs arbres. Les arbres sont sauvegardés dans le format natif du logiciel, les échanges en format PDF. Les arbres sont associés manuellement dans les dossiers patients.

Ces différentes versions autorisent des scenarii d’intégration d’une grande variété permettant de répondre au mieux aux attentes de nos clients et partenaires éditeurs de logiciels. Les cas d’utilisation sont nombreux, l’encadré ci-dessus vous en donne un aperçu qui, je l’espère, vous donnera des idées pour vos projets.

Laurent ROSSAERT – PC PAL
Director of Sales and Marketing
laurent.rossaert@pcpal.eu | LinkedIn

 

How to print complex pedigrees with PedigreeXP

When you have to deal with complex pedigrees, printing can become as complex as the family but not with PedigreeXP! Thanks to a smart printing engine, printing is easy and customizable.

To customize the printing area, right click on the Pedigree drawing and choose “Set print area”.

 

Print a complex pedigree with PedigreeXP - Set printing area

Print a complex pedigree with PedigreeXP – Set printing area

 

What you can customize:

  • Divide the pedigree into several pages and change their size. You can move the print area by dragging the horizontal or vertical lines with the mouse. Moving the print area increases or decreases the amount of pages to be printed.
  • Choose the page layout: you can set whether you want to perform the printing in landscape or portrait mode by clicking on the arrow (displayed in the middle of each page).
  • Select only the pages you want to print: with complex and large pedigrees there might be parts of the drawing that are unnecessary to print. To deselect pages, untick the box in the middle of the page that should not be printed. The page will turn grey.
Print a complex pedigree with PedigreeXP - Customize your printing

Print a complex pedigree with PedigreeXP – Customize your printing

 

When you are satisfied with your print layout, click on the print icon in the upper left navigation section, a print preview opens and a toolbar enables you to:

Print a complex pedigree with PedigreeXP - Printing toolbar

Print a complex pedigree with PedigreeXP – Printing toolbar

  • Zoom to page width or height
  • Flip through the pages to make sure you are satisfied with their layout.
  • Click on the print icon from the toolbar to print

In addition:

  • Export the pedigree as PDF
  • Copy the pedigree to Clipboard as an image
  • Copy the pedigree data to Clipboard

 

To print simpler pedigrees, it is possible to print directly from the navigation window (top left corner) or from the properties panel. PedigreeXP will optimize the printing layout of your pedigree drawing and print all pages directly.

Check PedigreeXP other features or download a free trial

How to automatically detect carrier females of X-linked condition with PedigreeXP?

With PedigreeXP, detect at a glance the X-linked disease carrier females. Refine the diagnosis to inform the family about the risks for their descendants.

PedigreeXP has a feature for automatic detection of carrier females when the X-rules setting is applied. The feature can be switched on in the properties panel: Apply X rules.

PedigreeXP - Properties panel with X-rules setting applied.

PedigreeXP – Properties panel with X-rules setting applied.

 

X-linked recessive traits are not clinically manifested when there is a normal copy of the gene. The X-chromosome is always transmitted from an affected father to his daughter and PedigreeXP can therefore help the users by automatically marking them as carriers.

PedigreeXP - Affected Father, daughters will automatically be detected as carriers.

PedigreeXP – Affected Father, daughters will automatically be detected as carriers.

 

A carrier mother who has a mutation in a gene on the X chromosome can transmit the X chromosome with this mutation to her children. PedigreeXP will help the user by applying a suspicion to the children until more information can be entered.

PedigreeXP - Carrier mother with three children.

PedigreeXP – Carrier mother with three children.

 

Check PedigreeXP other outstanding features. If you need assistance, contact us at sales@pedigreexp.com.

 

How to set multiple relationships and marriages in PedigreeXP?

When it comes to complex family tree, PedigreeXP is your best ally. With  just a few clicks, easily draw complex and multiple relationships spanning over generations, to better visualize the family history and the risks that may result.

PedigreeXP - Complex relationships spanning over generations

PedigreeXP – Complex relationships spanning over generations

 

To begin, you should always start with linking two persons as ” Spouse” as the default relationship type is set to “marriage”.

To do so, select a member and the hint with the relationship type “Spouse” will appear. Click on the “+Spouse” button and a spouse icon will automatically be added.

PedigreeXP - Add a "Spouse" relatonship type

PedigreeXP – Add a “Spouse” relatonship type

 

Then, you will be able to add the relationship type: marriage, concubinage, divorce, separation, consanguinity. To do so, select two people at the same time by a “click and drag” with the mouse. You can also select two people by holding the “Shift” key and clicking on the icons at the same time. Both persons are now selected as they are highlighted with a blue square. Mouse over one of the icons to open the hint which displays the available family connections.

Click on the icon that represents the relationship type you need.

PedigreeXP - Where to select the relationship type

PedigreeXP – Where to select the relationship type

 

To remove a family relationship, simply click on the “- Spouse” button.

PedigreeXP - Remove the "Spouse" relationship type

PedigreeXP – Remove the “Spouse” relationship type

 

It is also possible to manage the relationship type setting from the data entry panel on the right side of the tree.

PedigreeXP - Setting relationships from the data entry panel

PedigreeXP – Setting relationships from the data entry panel

 

Check PedigreeXP other outstanding features.

If you need assistance, contact us at sales@pedigreexp.com.

How to customize data in PedigreeXP?


(EN | FR)

Protect your patients’ data is a duty. But the collaboration with your colleagues is essential in your practice. When you draw a tree, you should be able to select the information you want to display or not when you decide to share it. PedigreeXP display settings respond to this requirement.

PedigreeXP offers different display settings options to customize the data display to the users’ best interests. You can open the display settings dialogue via the cogwheel in the top right corner.

Display settings - cogwheel

Display settings – cogwheel

In the dialogue, you can choose which information labels you want to display for a family member.

You can select up to four labels to be displayed underneath a person and one on the left and one on the right. It is also possible to change the order of labels, to even further customize the information display.

PedigreeXP - Display Settings panel

PedigreeXP – Display Settings panel

 

Before clicking OK, the user will always be able to see the changes in real time behind the dialogue and check if the settings are suitable.

Check PedigreeXP other outstanding features.

 


Comment paramétrer l’affichage de vos données avec PedigreeXP ?

(EN | FR)

La protection des données de vos patients est une obligation. Mais la collaboration avec vos collègues est essentielle dans votre pratique. Lorsque vous dessinez un arbre généalogique, vous devez pouvoir choisir les informations que vous souhaitez faire apparaître ou non lorsque vous décidez de les partager. Le paramétrage d’affichage des données dans PedigreeXP répond à ce besoin.

PedigreeXP propose différentes options d’affichage pour satisfaire au mieux les besoins de ses utilisateurs. Pour accéder à ce paramétrage, cliquez sur le symbole “engrenage” qui se situe en haut à droite de l’écran de l’application.

Display settings - cogwheel

Display settings – cogwheel

Dans la boîte de dialogue, vous pouvez choisir les types de données que vous souhaitez afficher pour une famille.

Vous pouvez sélectionner jusqu’à quatre types de données qui s’afficheront sous la personne, un type de données pour la droite et un autre pour la gauche. Il est aussi possible de changer l’ordre des données pour en affiner leur affichage.

PedigreeXP - Display Settings panel

PedigreeXP – Display Settings panel

Avant de cliquer sur OK, l’utilisateur pourra toujours voir les changements en temps réel en arrière-plan de la boîte de dialogue pour vérifier que ses paramétrages lui conviennent.

Découvrir les autres fonctionnalités de PedigreeXP.

Annual Clinical Genetics Meeting in Tampa – March 9-11, 2016

Come and meet us at the Annual Clinical Genetics Meeting in Tampa on March 9-11, 2016 – Booth 926.

Meet PC PAL at the Annual Clinical Genetics Meeting on March 9-11 in Tampa - booth 926!

Meet PC PAL at the Annual Clinical Genetics Meeting on March 9-11 in Tampa – booth 926!

Take a minute to discover PedigreeXP, the #1 pedigree drawing and managing software and get your free trial!
Make the most of this event to meet with our experts. Please contact us or call 00 33 1 69 53 46 20 to plan a meeting ahead.
We’re at booth #926!
Check PedigreeXP features – Download a free trial

8èmes Assises de Génétique Humaine et Médicale 2016

Rencontrons-nous à la 8ème édition des « Assises de Génétique Humaine et Médicale » à Lyon, 3-5 février 2016

Nous sommes impatients de présenter à la communauté française la dernière version de PedigreeXP, l’outil de dessin et de gestion d’arbres génétiques le plus précis et le plus rapide.

Avec des fonctionnalités exceptionnelles, PedigreeXP offre des bénéfices tangibles et immédiats à ses utilisateurs :

  • Dessiner un arbre génétique en quelques secondes durant les consultations
  • Identifier les risques familiaux concernant certaines maladies
  • Saisie unique et synchronisation des données avec les systèmes de dossiers patients hospitaliers
  • Gestion facilitée d’arbres génétiques complexes

Prenez une minute sur le stand n° 20 pour découvrir PedigreeXP et obtenir votre version d’essai gratuite sur ​​une clé USB !

Posez directement vos questions à nos spécialistes !

Si vous souhaitez planifier une rencontre à cette occasion, contactez-nous à sales@pedigreexp.com.

Rencontrez PC PAL aux 8èmes assises de Génétique Humaine et Médicale - 3 au 5 février 2016 à Lyon

Rencontrez PC PAL aux 8èmes assises de Génétique Humaine et Médicale – 3 au 5 février 2016 à Lyon

Meet PC PAL at the « Assises de Génétique Humaine et Médicale » conference in Lyon, February 3 – 5, 2016.

We are eager to meet with our French followers and present the latest version of PedigreeXP, the fastest and the most accurate pedigree drawing and management tool.

Thanks to outstanding features, PedigreeXP offers tangible and immediate user benefits:

  • Pedigree drawing in seconds during consultations
  • Risks identification for family disorders
  • Unique data entry and data synchronization when integrated into EMR systems
  • Complex pedigrees easy management

Take one minute on booth #20 to discover PedigreeXP and get your free trial on a USB flash drive!

Ask your questions directly to our specialists!

If you wish to plan in advance a meeting, contact us at sales@pedigreexp.com.

We look forward to meeting with you!